How might one calibrate the molecular clock to an absolute time clock

How might one calibrate the molecular clock to an absolute time clock. With the help of merging details about the absolute age or the age nodes, we can calibrate the molecular clock.

The present process for calibrating the molecular clock is related to the complete confirmation of the model of the dating bond with the morphological model.

The molecular clock is the most vital part of that phylogenetical analysis. We use the molecular clock for measuring evolutionary changes.

By calculating the protein difference, the scientist calibrates the pair of organisms using nucleotide sequence. The evolutionary rate present in proteins is known and is also used to check the results with the help of a given nucleotide protein.

How can one make the Calibration of a Molecular Clock into an Absolute Time Clock

The data that use for calibrating the molecular clock is fossil records. The fossil records are beneficial for the calibrating nodes within the geological time drop. It is the most used source for calibrating molecular clocks. The rate for the evolution does not change for the sequence of the absorption.

The wristwatch gives measurements for regular changes in the molecular clocks for random changes. The molecular clocks usually face problems because of taxa which is the absence of a fossil record.

When fossil fuel separation is not present, you can use the geological or biogeographic occurrence. The molecular clock generally gives more errors. It does not provide accuracy in evolutionary time.

Accessibility of the data helps the molecular clock to work efficiently. The character with which it evolved at a constant rate is reliable for the molecular clock. You should know about the molecular clock’s calibration and the time approximation. You can have information about these two species when you see the gene sequence for the taxa and those linked to the taxa.

For a shorter time, there is the use of clams and squid instead of clams and snails. The molecular clocks give the lines connected with the genetic distance and the estimation separation.

What is Molecular Clock

The molecular clocks have become a vital component of evolutionary biology and conservation genetics. It mainly contacted the organisms. The genetic difference among the species is directly related to the time used by these species. The hypothesis for the molecular scale is fundamental in the approximation of the timescales.

The molecular clock is straightforward because the rate of evolution varies among organisms. The molecular-scale can run within the short or very long timescale. But at a long time scale, the problem of saturation occurs. When more time passes, the site can go through some changes.

Calibrating the Molecular Clock

To calibrate the molecular scale, we have to know the certain ages for some separation events in the situation among birds and mammals—the approximation of the timing of this event is understandable with the help of the fossil record. The evolutionary rate is measurable with the calibration of the molecular clocks.

For calculating the evolutionary rate, we use the one group of organisms we make a comparison with the other group, and it can also compare the species that are the same. The time duration of the molecular cycle is twice as compared to others.

There are two processes available for the calibration of molecular records using fossil records are:

  • Tip Calibration

It is also named tip dating. The tip calibration is a process in which the taxa of fossil records are examined and then put on the tips of the tree.

Not unlike the node calibration, it reconstructs the tree topology. This process never depends upon negative evidence. The total evidence rating is near the tip calibration, which can be approvable by putting it into models.

  • Node calibration

it is also named the node dating. It performs the calibration process by locating the fossil records on its node. The maximum clade age should be estimated using the molecular scale for calibration analysis.

Recognition of the full clade age is problematic because it depends on the negative evidence, which means that fossil records are not present in the clade.


The molecular-scale use in molecular systematics; uses molecular genetic details to check the accurate scientific allocating of the organisms.

Biogeographic events are beneficial in calibrating the details of the molecular clocks when other calibrating sources are unavailable. Understanding the biogeographic’s potential and limitations helps improve the efficiency of molecular approximation in the evolutionary rates and the time scale.

Leave a Comment